| Product description: |
Migraine: Clinically tested ingredients for preventing vascular head discomfort.
- Riboflavin, which may help correct certain mitochondrial dysfunctions related to head discomfort, has also been effective in a controlled clinical study (Neurology 1998;50:466-70).
- Magnesium participates in the regulation of vascular tone and reactivity, acts as a mild calcium channel blocker, and influences the effects of serotonin and other neurotransmitters, as well as platelet function and inflammatory mechanisms (Persp Biol Med 1988;31:526-557).
- Magnesium supplementation helps increase days without head discomfort according to several controlled clinical studies (Headache 1991;31:298-301, Fortschr Med 1994;112:328-330, Cephalalgia 1996;16:257-263).
- Magnesium is important for normal vascular function and supports healthy blood pressure (Hypertension 1998;32:260-5.) and optimal leg circulation (Vasa 1985;14:285-8).
- The magnesium component, normally found in high levels in the brain, participates in maintaining the equilibrium of the central nervous system and promoting healthy lipid metabolism.
- Magnesium is an essential nutrient having well-recognized effects on neuromuscular function, although clinical studies of these effects are lacking, experimental information suggest that magnesium has a special role in opposing neuromuscular hyperexcitability, as its insufficiency can lead to muscle cramping, nervous excitability, agitation, irritability, restlessness, anxiety and anxious depression.
- Feverfew herb contains chemical components with significant prostaglandin and serotonin-modifying effects that reduce the likelihood of physiologic events leading to head discomfort (Prog Med Chem 1992;29:217-38, Public Health Nutr 2000;3:509-14).
- Standardized feverfew leaf extract contains the active constituent, parthenolide, which has been shown to maintain normal blood vessel tone by reducing the release of serotonin from platelets. (Lancet 1985;1:1071-4).
- Feverfew inhibits the production and release of inflammatory chemicals such as prostaglandins and arachidonic acid (Prostagland Leukotrienes Med 1982;8:653-60).
- In addition to controlling platelet serotonin secretion, feverfew has been shown to reduce platelet aggregation (J Pharm Pharmacol 1990;42:553-7).
- Controlled clinical research has found feverfew effective for stabilizing cerebral vasomotor and nerve overactivity associated with certain musculoskeletal complaints (Cephalagia 1998;18:704-8).
Natural sources, hypoallergenic. |